5-Amino-1MQ 5mg: Product Details, Quality and Ordering
5-Amino-1MQ is often listed beside research peptides, but it is not a peptide. It is a small molecule, 5-amino-1-methylquinolinium, studied as an inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT). Preclinical research has examined it in adipose tissue, metabolism and ageing muscle models.
At Peptide King, our 5-Amino-1MQ 5mg is listed as a lyophilized research material. The current page states a 5mg nominal quantity, ≥98% HPLC-verified purity, and storage at -20°C protected from light. It is supplied exclusively for in-vitro laboratory research.
This guide explains what 5-Amino-1MQ is, what researchers have studied, and which quality details deserve attention before laboratory use.
What Is 5-Amino-1MQ?
5-Amino-1MQ is a methylquinolinium compound. Its structure is a quinoline ring system with a methyl group on the ring nitrogen and an amino group at position 5.
It Is a Small Molecule, Not a Peptide
Peptides are chains of amino acids. 5-Amino-1MQ contains none. Searches for “5 amino 1mq peptide” reflect where the compound is usually sold, not what it is chemically.
That matters for testing, because the analytical questions for a small molecule are different from those for a peptide sequence.
The Salt Form Changes the Numbers
The methylquinolinium portion carries a positive charge, so the compound is supplied as a salt.
Commercial reference standards list the iodide salt with the formula C10H11N2·I and a molecular weight of 286.11 g/mol. A different counter-ion would give a different molecular weight, so the salt form should be stated alongside any quantity or purity result.
What Has 5-Amino-1MQ Research Actually Studied?
Published 5-Amino-1MQ research is preclinical. That distinction should remain visible whenever the compound is discussed.
NNMT Sits Between Methylation and NAD+ Metabolism
NNMT transfers a methyl group from S-adenosylmethionine (SAM) to nicotinamide. Nicotinamide is also a precursor in the NAD+ salvage pathway, so NNMT activity sits at a junction between methylation and NAD+ metabolism.
A 2014 Nature study by Kraus and colleagues reported that reducing NNMT expression in adipose tissue and liver protected mice against diet-induced obesity. That work helped make NNMT a metabolic research target.
Diet-Induced Obesity Models
A 2018 Biochemical Pharmacology study by Neelakantan and colleagues reported that NNMT inhibitors, including 5-amino-1MQ, increased intracellular NAD+ and SAM and suppressed lipogenesis in cultured adipocytes.
In diet-induced obese mice, treatment was associated with lower body weight, reduced white adipose mass and smaller adipocytes. These were mouse findings, not human outcomes.
Ageing Muscle Models
A 2019 study from the same research group reported that NNMT inhibition supported muscle stem cell activity and muscle regeneration in aged mice.
How Strong Is the Human Evidence for 5-Amino-1MQ?
The published literature consists of cell studies and animal models. We have not identified published clinical trials of 5-Amino-1MQ in humans.
5-Amino-1MQ therefore has an interesting preclinical rationale but no established human efficacy or safety profile. Peptide King presents it as laboratory research material, not a medical treatment.
What Does the Peptide King 5-Amino-1MQ 5mg Page Specify?
The live 5-Amino-1MQ 5mg research product page gives researchers several specifications directly.
The Listed Specifications
The current page identifies:
- Quantity: 5mg
- Form: lyophilized powder
- Purity: ≥98% HPLC verified
- Storage: -20°C protected from light
- Compound class: small-molecule NNMT inhibitor
What the Current 5-Amino-1MQ Page Does Not Show
The page does not state the salt form or molecular weight, and it does not display a batch-specific CoA link.
For a charged small molecule, those details belong together. Before relying on purity or quantity, confirm the salt form and match the analytical report to the lot being ordered.
HPLC Purity Is Not the Same as Identity
HPLC can estimate chromatographic purity by separating components in a sample. It does not establish that the main peak is 5-Amino-1MQ.
Mass spectrometry and NMR can support structural identity for a small molecule, while quantity testing answers a separate question.
Why Does a Certificate of Analysis Matter for 5-Amino-1MQ?
A CoA should connect analytical testing to the actual material being procured.
The Counter-Ion Should Be on the Report
Because molecular weight depends on the salt form, the certificate should name the full compound, not only the active cation.
Researchers should look for:
| CoA field | What to verify |
|---|---|
| Chemical name | Full name including salt form |
| Molecular weight | Consistent with the stated salt |
| Lot number | Matches current inventory |
| Purity | Method and result are reported |
| Identity | MS or NMR support is shown |
| Quantity | Measured content is distinguished from purity |
| Test date | Relevant to the current batch |
How Does 5-Amino-1MQ Relate to Other Metabolic Research Compounds?
5-Amino-1MQ is often discussed alongside NAD+ research because of the NNMT connection.
Related Pathways Do Not Make Compounds Interchangeable
Peptide King also lists NAD+ 500mg, the coenzyme itself, and MOTS-c 20mg, a mitochondrial-derived peptide studied in metabolic regulation.
5-Amino-1MQ is studied for its effect on an enzyme, NAD+ is a coenzyme, and MOTS-c is a peptide. They can appear in overlapping research areas, but a good experiment starts with the specific molecule.
How Does Canadian Fulfillment Work?
Peptide King fulfills research orders within Canada.
Domestic Processing Follows the Site’s Standard Timeline
The site states that orders are typically processed within one to two business days, with standard shipping estimated at three to seven business days depending on province. Tracking is provided after dispatch.
How We Present 5-Amino-1MQ 5mg at Peptide King
At Peptide King, we present 5-Amino-1MQ as a small-molecule research compound with a focused, preclinical evidence base.
It is not a peptide, and its quality questions start with chemistry rather than sequence.
Researchers should confirm the salt form, separate HPLC purity from identity and quantity, verify the lot, and keep mouse findings separate from human claims.
For research-grade 5-Amino-1MQ 5mg, the counter-ion is part of the quality check.